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Rs 6,930 Rs 5,250
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INTERSTITIAL DELETION OF THE LONG ARM OF CHROMOSOME 5 OCCURS AS A SOLE ABNORMALITY OR IN COMBINATION WITH ADDITIONAL ABERRATIONS IN MYELODYSPLASTIC SYNDROMES (MDS). IT IS SEEN IN 30% CASES OF PRIMARY MDS & 50% CASES OF SECONDARY MDS. 5Q-SYNDROME, A SUBTYPE OF LOW-RISK MDS, IS CHARACTERIZED BY AN ISOLATED 5Q DELETION AND <5% BLASTS IN THE BONE MARROW. HOWEVER, MDS PATIENTS WITH COMPLEX CHROMOSOMAL ABERRATIONS INCLUDING 5Q DELETION HAVE A POOR PROGNOSIS AND SHOW PROGRESSION TO ACUTE MYELOID LEUKEMIA (AML).
