MEDULLARY THYROID CARCINOMA MUTATION DETECTION

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MEDULLARY THYROID CARCINOMA MUTATION DETECTION

193 Ratings

Rs 19,500 Rs 15,000

23 % OFF

MUTATIONS (DNA CHANGES) IN THE RET PROTO-ONCOGENE, LOCATED ON CHROMOSOME 10, LEAD TO THE EXPRESSION OF A MUTATED RECEPTOR TYROSINE KINASE PROTEIN, TERMED RET (REARRANGED DURING TRANSFECTION). RET IS INVOLVED IN THE REGULATION OF CELL GROWTH & DEVELOPMENT AND ITS GERMLINE MUTATION IS RESPONSIBLE FOR NEARLY ALL CASES OF HEREDITARY OR FAMILIAL MEDULLARY THYROID CARCINOMA. ITS GERMLINE MUTATION MAY ALSO BE RESPONSIBLE FOR THE DEVELOPMENT OF HYPERPARATHYROIDISM AND PHEOCHROMOCYTOMA.

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