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An anti-nuclear antibody (ANA) profile is a blood test that detects antibodies produced by the immune system that mistakenly target the bodys own cell nuclei.Elevated ANA levels can indicate the presence of an autoimmune disease,
such as systemic lupus erythematosus (SLE),
rheumatoid arthritis,
or Sjogrens syndrome. The test measures both the presence and pattern of ANA, with different patterns associated with specific autoimmune conditions. A positive ANA test often requires further evaluation to confirm a diagnosis.