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The Anti-Soluble Liver Antigen (SLA) test is a blood test used to detect the presence of autoantibodies against a specific protein in the liver called the soluble liver antigen (SLA). These autoantibodies are often found in patients with autoimmune hepatitis, a condition where the body's immune system mistakenly attacks its own liver cells. The test helps diagnose autoimmune hepatitis, particularly type 1, and can be useful in monitoring disease activity and response to treatment.