A Brucella antibody IgG test detects the presence of IgG antibodies against Brucella bacteria in the blood. These antibodies indicate a past or current infection with Brucella, a bacteria commonly found in animals that can cause brucellosis in humans. While a positive result suggests exposure to the bacteria, it may not necessarily indicate an active infection as antibodies can persist after successful treatment. This test is essential for diagnosing brucellosis and monitoring treatment response.

WIDAL TEST IS USED TO DIAGNOSE TYPHOID AND PARATYPHOID FEVERS. A 4 FOLD RISE IN TITER IS DIAGNOSTIC OF INFECTION.

THIS ASSAY IS USED FOR EVALUATING PATIENTS WITH POSSIBLE INBORN ERRORS OF METABOLISM. IT MAY ALSO AID IN EVALUATION OF ENDOCRINE DISORDERS, LIVER DISEASES, MUSCLE DISEASES, NEOPLASTIC DISEASES, NEUROLOGICAL DISORDERS, NUTRITIONAL DISTURBANCES, RENAL FAILURE AND BURNS.

PROCOLLAGEN TYPE III AMINO TERMINAL PROPEPTIDE (PIIINP) HAS BEEN USED IN ASSESSMENT OF LIVER FIBROSIS, AS IT IS A MARKER OF EARLY FIBROGENESIS AND INFLAMMATION. METHOTREXATE (MTX) IS A WIDELY USED DRUG FOR THE TREATMENT OF PSORIASIS AND OTHER DERMATOLOGICAL CONDITIONS. MTX HAS BEEN RECOGNIZED TO BE HEPATOTOXIC WHICH LIMITS IT S THERAPEUTIC USE. THUS, MONITORING OF LIVER FOR STRUCTURAL AND FUNCTIONAL DAMAGE IS RECOMMENDED BEFORE AND DURING TREATMENT WITH MTX. PIIINP TEST CAN BE USED TO ASSESS MTX INDUCED LIVER TOXICITY, ESPECIALLY IN HIGH-RISK INDIVIDUALS LIKE PATIENTS WITH METABOLIC SYNDROME, NON-ALCOHOLIC FATTY LIVER DISEASE, EXCESSIVE ALCOHOL CONSUMPTION AND CHRONIC HEPATITIS B & C. THIS TEST HAS A SENSITIVITY OF 77% AND SPECIFICITY OF 92% IN ASSESSMENT OF LIVER TOXICITY IN MTX TREATED PATIENTS WITH PSORIASIS.