FISH: 22q DELETION OR LSI Di GEORGE / VCFS

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FISH: 22q DELETION OR LSI Di GEORGE / VCFS

140 Ratings

Rs 7,560 Rs 5,600

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DELETIONS IN 22Q11.2 HAVE BEEN ASSOCIATED WITH SEVERAL DISORDERS INCLUDING DIGEORGE SYNDROME (DGS) AND VELOCARDIOFACIAL SYNDROME (VCFS). IN THIS DISORDER A SMALL PART OF CHROMOSOME 22 IS MISSING, RESULTING IN MULTIPLE DEVELOPMENTAL DEFECTS SUCH AS CLEFT PALATE, POOR IMMUNE SYSTEM, HEART DEFECTS, DISTINCTIVE FACIAL FEATURES & LOW CALCIUM IN BLOOD. THE INHERITANCE OF 22Q11.2 DELETION SYNDROME IS AUTOSOMAL DOMINANT BUT MORE OFTEN THE DELETION IS A RANDOM EVENT.

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