146 Ratings
Rs 16,900 Rs 13,000
23 % OFF
CONVENTIONAL CYTOGENETICS DETECTS ABNORMAL KARYOTYPE IN 40% NEWLY DIAGNOSED MYELOMA CASES. BASED ON CONVENTIONAL KARYOTYPING THERE ARE TWO PROGNOSTIC GROUPS: HYPERDIPLOID (48-75 CHROMOSOMES ) ASSOCIATED WITH FAVOURABLE PROGNOSIS AND NON-HYPERDIPLOID (<48 & >75 CHROMOSOMES) ASSOCIATED WITH AN UNFAVOURABLE PROGNOSIS. ABNORMALITIES DETECTED BY FISH AFTER POSITIVE SELECTION OF CD138 CELLS, HAS PREDICTIVE USEFULNESS NAMELY- HIGH RISK DISEASE: IF T(14:16), T(14;20), DEL17P & DEL1P DETECTED; STANDARD RISK DISEASE: IF T(11:14), T(6;14) &/OR TRISOMIES DETECTED; INTERMEDIATE RISK: IF T(4;14) & GAIN(1Q21) DETECTED.
