FISH: t(15;17) OR LSI PML/RARA

141 Ratings

Rs 5,719 Rs 4,300

25 % OFF

ACUTE PROMYELOCYTIC LEUKEMIA (APL) IN ITS TYPICAL PRESENTATION EXPRESSES PML-RARA REARRANGEMENT DUE TO TRANSLOCATION T(15;17), AS SEEN IN 95% OF PATIENTS. THESE PATIENTS HAVE GOOD CLINICAL OUTCOME ON TREATMENT WITH DIFFERENTIATION THERAPY COMPRISING OF ALL-TRANS RETINOIC ACID ATRA & ATO. EARLY DIAGNOSIS & IMMEDIATE TREATMENT OF APL IS ESSENTIAL AS IT IS A MEDICAL EMERGENCY WHICH MAY LEAD TO COMPLICATIONS SUCH AS INTRA-VASCULAR COAGULATION & CEREBRAL HAEMORRHAGE.

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FISH: t(15;17) OR LSI PML/RARA

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