IMMUNOHISTOCHEMISTRY: CYCLIN-D1

IMMUNOHISTOCHEMISTRY: CYCLIN-D1

164 Ratings

Rs 2,790 Rs 2,130

24 % OFF

CYCLIN-D1 IS ONE OF THE MEMBERS OF CELL CYCLE PROTEINS THAT DRIVES THE TRANSITION BETWEEN G0 & G1 PHASE. IN NORMAL TISSUES, BASAL EPITHELIAL CELLS, ENDOTHELIAL CELLS & STROMAL CELLS ARE OFTEN CYCLIN-D1 POSITIVE. DUE TO TRANSLOCATION INVOLVING CYCLIN-D1 GENE & IGH, MAJORITY OF MANTLE CELL LYMPHOMAS OVEREXPRESS CYCLIN-D1. THIS IS A USEFUL FEATURE IN THE CLASSIFICATION OF LOW GRADE B CELL LYMPHOMAS.

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SUBMIT TISSUE IN 10% FORMAL-SALINE OR FORMALIN FIXED PARAFFIN EMBEDDED TISSUE BLOCK. SHIP AT ROOM TEMPERATURE. PROVIDE A COPY OF THE HISTOPATHOLOGY REPORT, SITE OF BIOPSY AND CLINICAL HISTORY.

IHC

REPORT ON 4TH DAY EVENING 7PM

PROVIDE A COPY OF THE HISTOPATHOLOGY REPORT, SITE OF BIOPSY AND CLINICAL HISTORY.

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