10 mL (5 mL min.) aliquot of random Urine collected in an acid washed (metal free) container kit available from TrueMedix. Ship refrigerated or frozen. Use powderless gloves during specimen collection. If Gadolinium or Iodine containing contrast media has been administered, the specimen should not be collected for 96 hours.
Sample Daily by 6 pm; Report Next day
Increased urine lead excretion rate indicates significant lead exposure. Measurement of urine lead excretion rate before and after chelation therapy has been used as an indicator of lead exposure. An increase in lead excretion rate in the postchelation specimen of up to 6 times the rate in the prechelation specimen is normal. Blood lead is the best clinical correlate of toxicity.
If Gadolinium or Iodine containing contrast media has been administered, specimen should not be collected for 96 hours.