Manganese is a trace element that is an essential cofactor for several enzymes. Environmental sources of Manganese can lead to toxicity. This assay is useful for evaluating central nervous system symptoms similar to Parkinson’s disease in manganese miners and processors. It is also useful for therapeutic monitoring of Cirrhosis, environmental exposure to manganese and nutrition related manganese toxicity. It also helps to evaluate Behcet’s disease. This is the recommended test for monitoring therapy.

4 mL (2 mL min.) Whole blood from 1 metal free Royal Blue Top (K2EDTA) tube available from TrueMedix. Ship refrigerated. DO NOT FREEZE. Patients should refrain from vitamins, mineral or herbal supplements one week prior to specimen collection. Use powderless gloves during specimen collection. If Gadolinium or Iodine containing contrast media has been administered, the specimen should not be collected for 96 hours.

ICPMS

Sample Daily by 6 pm; Report 2 days

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Avoid vitamins, mineral or herbal supplements one week prior to specimen collection. If Gadolinium or Iodine containing contrast media has been administered, specimen should not be collected for 96 hours.