TSH (THYROID STIMULATING HORMONE) IS A HORMONE PRODUCED BY THE PITUITARY GLAND THAT REGULATES THYROID FUNCTION. IT STIMULATES THE THYROID GLAND TO PRODUCE THYROID HORMONES, WHICH CONTROL METABOLISM, BODY TEMPERATURE, AND HEART RATE. ABNORMAL TSH LEVELS CAN INDICATE THYROID DISORDERS SUCH AS HYPERTHYROIDISM (OVERACTIVE THYROID) OR HYPOTHYROIDISM (UNDERACTIVE THYROID). BY MEASURING TSH, HEALTHCARE PROVIDERS CAN DIAGNOSE AND MONITOR THYROID CONDITIONS.

A 17-Hydroxyprogesterone (17-OHP) test measures the level of this hormone in your blood. 17-OHP is a precursor to cortisol, a hormone essential for managing stress. Primarily used to diagnose Congenital Adrenal Hyperplasia (CAH), a genetic disorder affecting the adrenal glands, this test helps assess the bodys ability to produce cortisol.Elevated 17 - OHP levels can indicate CAH, while low levels might suggest other adrenal gland issues.This test is crucial for newborn screening and monitoring treatment for individuals with CAH.

IT IS USED TO DEFINITIVELY DIAGNOSE G6PD DEFICIENCY, A GENETIC DISORDER THAT CAN CAUSE A SEVERE TYPE OF ANEMIA CALLED HEMOLYTIC ANEMIA IN RESPONSE TO CERTAIN MEDICATIONS, FOODS, OR INFECTIONS.

NEWBORN SCREENING PROVIDES AN OPPORTUNITY FOR EARLY DETECTION OF SICKLE CELL DISEASE, SOME SEVERE FORMS OF THALASSEMIA AND MANY COMMON VARIANTS (HBC, HBE, HBDPUNJAB ETC). IN OUR COUNTRY, HEMOGLOBINOPATHIES ARE AN IMPORTANT CAUSE OF GENETIC MORBIDITY AND MORTALITY. IT IS ESSENTIAL THAT INFANTS WITH THESE CONDITIONS ARE RELIABLY DIAGNOSED SO THAT THE EARLY TREATMENT AND NECESSARY CLINICAL FOLLOW UP IS INITIATED.