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THE PRE-TRANSPLANT LYMPHOCYTE CROSSMATCH IS A CRUCIAL TEST PERFORMED BEFORE ORGAN TRANSPLANTATION TO ASSESS THE COMPATIBILITY BETWEEN THE DONOR AND RECIPIENT. IT INVOLVES MIXING THE RECIPIENTS SERUM WITH THE DONORS LYMPHOCYTES. A POSITIVE CROSSMATCH, INDICATING THE PRESENCE OF RECIPIENT ANTIBODIES AGAINST THE DONORS LYMPHOCYTES, IS A CONTRAINDICATION FOR TRANSPLANTATION AS IT CAN LEAD TO HYPERACUTE REJECTION, A RAPID AND SEVERE FORM OF GRAFT REJECTION. A NEGATIVE CROSSMATCH, ON THE OTHER HAND, SUGGESTS COMPATIBILITY AND ALLOWS FOR THE TRANSPLANT TO PROCEED.SOURCES AND RELATED CONTENT
