SCA (SPINOCEREBELLAR ATAXIA) PROFILE: ANY 4 MARKERS

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SCA (SPINOCEREBELLAR ATAXIA) PROFILE: ANY 4 MARKERS

182 Ratings

Rs 9,900 Rs 7,500

24 % OFF

SPINOCEREBELLAR ATAXIA (SCA) ARE AUTOSOMAL DOMINANT CEREBELLAR ATAXIAS OF VARIOUS TYPES RANGING FROM 1 TO 40. SCA1, 2, 3, 6, 7 & 17 ARE CAUSED BY CAG TRIPLET REPEAT EXPANSIONS IN DIFFERENT GENES. SCA8 IS DUE TO AN UNTRANSLATED CTG REPEAT EXPANSION; SCA12 IS LINKED TO AN UNTRANSLATED CAG REPEAT; SCA10 IS CAUSED BY AN UNTRANSLATED PENTANUCLEOTIDE REPEAT. THE CLINICAL PHENOTYPES OF SCAS OVERLAP, HENCE GENOTYPE HAS BECOME THE GOLD STANDARD FOR DIAGNOSIS AND CLASSIFICATION.

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