ANCA ( Antineutrophil Cytoplasmic Antibodies ), IFA is a blood test used to detect antibodies that mistakenly attack the bodys own white blood cells. These antibodies are associated with certain autoimmune diseases, particularly vasculitis, which causes inflammation of blood vessels. The IFA (Immunofluorescence) method involves examining a sample of blood under a microscope for the presence of these antibodies. Positive results can help diagnose specific types of vasculitis and monitor disease activity.

The anti-dsDNA (double-stranded DNA) ELISA is a blood test used to detect antibodies that mistakenly target the body's own DNA. Elevated levels of these antibodies are strongly associated with systemic lupus erythematosus (SLE), an autoimmune disease. The test involves coating a plate with dsDNA, adding the patient's blood sample, and detecting any bound antibodies using an enzyme-linked reaction. A positive result can aid in the diagnosis of SLE and help monitor disease activity.

PR-3 OR C-ANCA ANTIBODY IS OFTEN SEEN IN WEGENERS GRANULOMATOSIS, A NECROTISING GRANULOMATOUS VASCULAR DISEASE TYPICALLY INVOLVING THE RESPIRATORY TRACT AND KIDNEYS.