2 mL (1 mL min.) Serum from 1 SST. Ship refrigerated or frozen. Overnight fasting is preferred.
Sample Daily by 11 am; Report Next day
This assay is useful for evaluating patients suspected of having Autoimmune vasculitis, both Wegeners granulomatosis and Microscopic Polyangiitis. Autoantibodies to PR3 (c-ANCA) occur in patients with classical limited end-organ involvement Wegeners granulomatosis. Antibodies to MPO (p-ANCA) occur predominantly in patients with Microscopic Polyangiitis.