Administer tablet 1 mg Dexamethasone orally at 11 pm at night. Draw 2 mL (1 mL min.) Serum from 1 SST at 8 am next morning. Ship refrigerated or frozen.
Overnight dexamethasone suppression test checks the effect of dexamethasone on cortisol levels in the blood. This is a screening test to document true hypersecretion of cortisol. Patients with Cushings syndrome of any cause will fail to suppress their cortisol secretion with a low dose of dexamethasone.
Patient to take tablet Dexamethasone orally at 11 pm at night and come for test next morning at 8 am. Patient should not be on steroid therapy.