In DIC both thrombin and plasmin are generated. The breakdown products of fibrin clots and fibrinogen include D-Dimer and FDP. These analytes are also elevated when the coagulation and fibrinolytic systems are activated.

3 mL Whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. ; transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. ; finally transfer the supernatant (PPP) to 1 labelled, clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Latex Agglutination

Daily

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Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.