5 mL (3 mL min.) Whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE. Duly filled Chromosome ; FISH analysis Requisition Form (Form 17) is mandatory.
FISH
Sample Daily by 4 pm; Report 4 Working days
Chromosome 13q long arm deletion is observed in patients with Multiple Myeloma and is associated with worse prognosis. Deletion 13q can also be found in a number of mature B-cell lymphoid neoplasms, particularly Chronic Lymphocytic Leukemia (CLL) and also Splenic marginal zone lymphoma ; Mantle cell lymphoma. It is rarely seen in Monoclonal gammopathy of undetermined significance (MGUS).
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Duly filled Chromosome ; FISH analysis Requisition Form (Form 17) is mandatory.