50 mL (10 mL min.) aliquot of random Urine. Add 50% HCl drop by drop to bring the pH between 1â€“2. Do not use concentrated HCl. Ship refrigerated or frozen. Patient should strictly avoid L-Dopa at least 72 hours before and during collection.
Sample by Wed Sat 9 am; Report on Fri Tue
HVA and other catecholamine metabolites are elevated in patients with Neuroblastoma, Pheochromocytoma and other Neural crest tumors. This assay is useful for screening of catecholamine secreting tumors, monitoring Neuroblastoma treatment and evaluating patients with possible inborn errors of catecholamine metabolism.
Strictly avoid L-Dopa at least 72 hours before and during collection.