Maternal serum screen 2 Advanced test is a screen test done between 10-13 weeks of pregnancy. It has significant utility in Prenatal Screening of Down Syndrome Trisomy 21. By reflexing Maternal Dual test with MBFD at chromosome 21, the specificity of the test increases to >99% with a false positive rate of <0.05%.

3 mL (1.5 mL min.) Serum from 1 SST. Provide maternal Date of birth (dd/mm/yy); LMP or Ultrasound; Number of Fetuses (Single/Twins); Diabetic status and Body Weight in Kg, IVF, Smoking & Previous history of Trisomy 21 pregnancy. Ship refrigerated or frozen. All positive results to submit 10 mL Whole blood in a Special tube available from TrueMedix for MBFD-21/NIPT along with duly filled Form G AND Maternal Serum Screen 2 reflex to MBFD-21 consent form (Form 12). Samples shall be accepted only from registered genetics clinics under PCPNDT Act. Ship refrigerated. DO NOT FREEZE. Valid between 10-13 weeks gestation.

CLIA, DNA Sequencing

Dual test: Sample Mon through Sat by 9 am; Report Same day MBFD-21: Sample Tue by 9 am; Report Next Tue

*PAPP-A *Free Beta HCG *Risk Evaluation *MBFD-21

Provide maternal Date of birth (dd/mm/yy); LMP or Ultrasound; Number of Fetuses (Single/Twins); Diabetic status and Body Weight in Kg, IVF, Smoking & Previous history of Trisomy 21 pregnancy. All positive results to submit 10 mL Whole blood in a Special tube available from TrueMedix for MBFD-21/NIPT along with duly filled Maternal Serum Screen 2 reflex to MBFD-21 consent form (Form 12). Valid between 10-13 weeks gestation.