25 %

Myeloproliferative Neoplasia With Eosinophilia

366 Ratings

Rs 18,000 Rs 23,940

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Test Description not updated

3 mL (2 mL min.) Whole blood from 1 Lavender Top (EDTA) tube AND 2 mL (1.5 mL min.) Bone marrow in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) Bone marrow in 1 Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT FREEZE. Duly filled Chromosome ; FISH Analysis Requisition form (Form 17) is mandatory.

Electrical impedence, Microscopy, FISH

Sample Daily by 4 pm; Report 7 Working days

Myeloproliferative neoplasia (MPN) with Eosinophilia has been categorized as a separate disease entity with the rearrangement of the genes - PDGFRA, PDGRB ; FGFR1 by the recent (2016) revision to the WHO classification of Myeloid neoplasms ; Acute leukemia. Identification of these dysregulated fusion Tyrosine kinase (TK) genes is crucial for the therapeutic strategy and prognostication of these otherwise BCR-ABL1 negative Myeloproliferative neoplasias. This panel is precisely designed to identify these Myeloproliferative neoplasias of clinical significance.

*CBC *Peripheral Smear *Bone Marrow Panel 1 *FISH for PDGFRA, PDGFRB, FGFR1

Duly filled Chromosome ; FISH Analysis Requisition form (Form 17) is mandatory.

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