3 mL (2 mL min.) Whole blood from 1 Lavender Top (EDTA) tube AND 2 mL (1.5 mL min.) Bone marrow in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) Bone marrow in 1 Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT FREEZE. Duly filled Chromosome ; FISH Analysis Requisition form (Form 17) is mandatory.
Electrical impedence, Microscopy, FISH
Sample Daily by 4 pm; Report 7 Working days
Myeloproliferative neoplasia (MPN) with Eosinophilia has been categorized as a separate disease entity with the rearrangement of the genes - PDGFRA, PDGRB ; FGFR1 by the recent (2016) revision to the WHO classification of Myeloid neoplasms ; Acute leukemia. Identification of these dysregulated fusion Tyrosine kinase (TK) genes is crucial for the therapeutic strategy and prognostication of these otherwise BCR-ABL1 negative Myeloproliferative neoplasias. This panel is precisely designed to identify these Myeloproliferative neoplasias of clinical significance.